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Cervicovaginal levels of human beta defensins during bacterial vaginosis

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dc.contributor Universidade Estadual Paulista (UNESP)
dc.creator Nicolau, Nathalia Mayumi Noda
dc.creator Silva, Márcia Guimarães da
dc.date 2021-07-27T17:39:24Z
dc.date 2021-07-27T17:39:24Z
dc.date 2021-07-22
dc.date.accessioned 2024-09-24T16:48:22Z
dc.date.available 2024-09-24T16:48:22Z
dc.identifier http://hdl.handle.net/11449/213676
dc.identifier 2925946803904487
dc.identifier 4940791909535775
dc.identifier 0000-0002-2392-6127
dc.identifier 00000002-4663-7926
dc.identifier.uri https://metabuscador.uspdigital.usp.br/xmlui/handle/doc/16374
dc.description A total of 634 women of reproductive age were included in the study. Participants were equally distributed in two groups: according to the classification of vaginal smears according to Nugent criteria in normal (scores 0 to 3) and BV (scores ≥7). Cervicovaginal fluid samples were used for measurements of hBDs1, 2 and 3 levels by enzyme-linked immunosorbent assay (ELISA). Levels of each hBD were compared between the two study groups using Mann-Whitney test, with p-value <0.05 considered as significant. Odds ratio (OR) and 95% confidence interval (95% CI) were calculated for sociodemographic variables and hBD1-3 levels associated with BV a multivariable analysis. Correlation between Nugent score and measured levels of hBDs1-3 were calculated using Spearman’s test.
dc.description Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.description FAPESP: 2012/16800-3
dc.format Excel
dc.format application/vnd.openxmlformats-officedocument.spreadsheetml.sheet
dc.language eng
dc.rights info:eu-repo/semantics/openAccess
dc.subject Human beta defensins
dc.subject Bacterial vaginosis
dc.title Cervicovaginal levels of human beta defensins during bacterial vaginosis
dc.type info:eu-repo/semantics/dataset


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