This dataset contains cardiovascular disease (CVD) death records from individuals from the city of Campinas, São Paulo, Brazil, during the period from 2001 to 2018, associated to environmental parameters obtained from weather stations in the dates of death. The information related to each death record includes the date, stratified causes of the death, age, sex, and race of the individuals. The environmental parameters include minimum, maximum and mean values of carbon monoxide (CO), particulate matter size 10 micrometers (PM10), air temperature, relative air humidity, air pressure.