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Analysis of the effects of simvastatin on the mevalonate pathway, cell wall integrity and bacterial metabolome: evidence of the antimicrobial mechanism of action

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dc.contributor.author Sousa, Iago Torres Cortês de
dc.contributor.author Silva, Kátia de Pádua
dc.contributor.author Müller, Karina Cogo
dc.coverage.spatial São Paulo, Brazi
dc.date 2022-04-12
dc.date.accessioned 2022-04-08
dc.date.accessioned 2022-04-13T10:12:02Z
dc.date.available 2022-04-13T10:12:02Z
dc.identifier.uri https://doi.org/10.25824/redu/TJVOA2
dc.identifier.uri https://redu.unicamp.br/dataset.xhtml?persistentId=doi:10.25824/redu/TJVOA2
dc.description These data are the result of research carried out to investigate the antimicrobial action mechanism of simvastatin against S. aureus. Analyzes were performed to verify changes in gene expression, cell wall integrity, metabolome, proteome and HMG-CoA-reductase II enzyme.
dc.description.sponsorship Fundação de Amparo à Pesquisa do Estado de São Paulo
dc.format text/tab-separated-values
dc.language English
dc.publisher Torres Cortês de Sousa, Iago
dc.subject Chemistry
dc.subject Medicine, Health and Life Sciences
dc.title Analysis of the effects of simvastatin on the mevalonate pathway, cell wall integrity and bacterial metabolome: evidence of the antimicrobial mechanism of action
dc.description.sponsorshipId FAPESP: 2018/20593-0


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