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Analysis of the effects of simvastatin on the mevalonate pathway, cell wall integrity and bacterial metabolome: evidence of the antimicrobial mechanism of action

Analysis of the effects of simvastatin on the mevalonate pathway, cell wall integrity and bacterial metabolome: evidence of the antimicrobial mechanism of action

Sousa, Iago Torres Cortês de; Silva, Kátia de Pádua; Müller, Karina Cogo
URI: https://doi.org/10.25824/redu/TJVOA2
https://redu.unicamp.br/dataset.xhtml?persistentId=doi:10.25824/redu/TJVOA2

Descrição:

These data are the result of research carried out to investigate the antimicrobial action mechanism of simvastatin against S. aureus. Analyzes were performed to verify changes in gene expression, cell wall integrity, metabolome, proteome and HMG-CoA-reductase II enzyme.

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