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Left ventricular geometry in COPD patients: are there associations with airflow limitation, functional capacity, and grip strength?

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dc.contributor.author Heubel, Alessandro Domingues
dc.contributor.author Roscani, Meliza Goi
dc.contributor.author Kabbach, Erika Zavaglia
dc.contributor.author Agnoleto, Aline Galvão
dc.contributor.author Camargo, Patrícia Faria
dc.contributor.author Santos, Polliana Batista dos
dc.contributor.author Silva, Audrey Borghi
dc.contributor.author Mendes, Renata Gonçalves
dc.date.accessioned 2022-02-09T10:13:37Z
dc.date.available 2022-02-09T10:13:37Z
dc.date.issued 2020-09
dc.identifier https://doi.org/10.1097/hcr.0000000000000483 por
dc.identifier.citation HEUBEL, Alessandro Domingues; ROSCANI, Meliza Goi; KABBACH, Erika Zavaglia; AGNOLETO, Aline Galvão; CAMARGO, Patrícia Faria; SANTOS, Polliana Batista dos; BORGHI-SILVA, Audrey; MENDES, Renata Gonçalves. Left ventricular geometry in COPD patients: are there associations with airflow limitation, functional capacity, and grip strength?. Repositório de Dados da UFSCar, 2020. Dataset. Disponível em: https://repositorio.ufscar.br/handle/ufscar/15569. *
dc.identifier.uri https://repositorio.ufscar.br/handle/ufscar/15569
dc.description Purpose: Chronic obstructive pulmonary disease (COPD) and abnormalities of left ventricular (LV) geometry often coexist. This study aimed to verify whether LV geometry is associated with airflow obstruction, functional capacity, and grip strength in COPD patients. Methods: Thirty-seven COPD patients (GOLD II, III, and IV) were allocated to three groups according to LV geometry as assessed by transthoracic echocardiography: normal (n = 13), concentric LV remodeling (n = 8), and concentric LV hypertrophy (LVH) (n = 16). Lung function was assessed using spirometry. The Duke Activity Status Index (DASI) was used to estimate functional capacity, and grip strength measurement was performed using a hydraulic hand dynamometer. Results: The concentric LVH group presented lower DASI scores (P = .045) and grip strength (P = .006) when compared with the normal group. Correlations analysis showed the following: relative wall thickness negatively correlated with forced expiratory volume in the first second (r = -0.380; P = .025) and DASI score (r = -0.387, P = .018); LV mass index negatively correlated with grip strength (r = -0.363, P = .038). Conclusions: In COPD patients, LV geometry is associated with airflow limitation, functional capacity, and grip strength. Specifically, concentric LV remodeling is associated with increased airflow limitation and decreased functional capacity whereas increased LV mass is associated with decreased grip strength. eng
dc.description.sponsorship Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) por
dc.description.sponsorship Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) por
dc.language.iso eng eng
dc.publisher Universidade Federal de São Carlos por
dc.relation.uri https://pubmed.ncbi.nlm.nih.gov/32804795/ por
dc.relation.uri https://repositorio.ufscar.br/handle/ufscar/11071
dc.rights Attribution-NonCommercial-NoDerivs 3.0 Brazil *
dc.rights.uri http://creativecommons.org/licenses/by-nc-nd/3.0/br/ *
dc.subject Chronic obstructive pulmonary disease eng
dc.subject Left ventricular hypertrophy eng
dc.subject Left ventricular remodeling eng
dc.subject Physical fitness eng
dc.title Left ventricular geometry in COPD patients: are there associations with airflow limitation, functional capacity, and grip strength? eng
dc.type Dataset eng
dc.description.sponsorshipId Processo nº 2018/03314-0, Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) por
dc.description.sponsorshipId Processo nº 2018/00860-3, Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) por
dc.description.sponsorshipId Processo nº 2015/26501–1, Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) por
dc.description.sponsorshipId Processo nº 2015/12763-4, Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) por
dc.description.sponsorshipId Código de Financiamento 001 - CAPES por


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Attribution-NonCommercial-NoDerivs 3.0 Brazil Exceto quando indicado o contrário, a licença deste item é descrito como Attribution-NonCommercial-NoDerivs 3.0 Brazil