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DOI:	https://doi.org/10.1097/hcr.0000000000000483
Título:	Left ventricular geometry in COPD patients: are there associations with airflow limitation, functional capacity, and grip strength?
Assunto:	Chronic obstructive pulmonary disease;Left ventricular hypertrophy;Left ventricular remodeling;Physical fitness
Descrição:	Purpose: Chronic obstructive pulmonary disease (COPD) and abnormalities of left ventricular (LV) geometry often coexist. This study aimed to verify whether LV geometry is associated with airflow obstruction, functional capacity, and grip strength in COPD patients. Methods: Thirty-seven COPD patients (GOLD II, III, and IV) were allocated to three groups according to LV geometry as assessed by transthoracic echocardiography: normal (n = 13), concentric LV remodeling (n = 8), and concentric LV hypertrophy (LVH) (n = 16). Lung function was assessed using spirometry. The Duke Activity Status Index (DASI) was used to estimate functional capacity, and grip strength measurement was performed using a hydraulic hand dynamometer. Results: The concentric LVH group presented lower DASI scores (P = .045) and grip strength (P = .006) when compared with the normal group. Correlations analysis showed the following: relative wall thickness negatively correlated with forced expiratory volume in the first second (r = -0.380; P = .025) and DASI score (r = -0.387, P = .018); LV mass index negatively correlated with grip strength (r = -0.363, P = .038). Conclusions: In COPD patients, LV geometry is associated with airflow limitation, functional capacity, and grip strength. Specifically, concentric LV remodeling is associated with increased airflow limitation and decreased functional capacity whereas increased LV mass is associated with decreased grip strength.
Autor(es):	Heubel, Alessandro Domingues Roscani, Meliza Goi Kabbach, Erika Zavaglia Agnoleto, Aline Galvão Camargo, Patrícia Faria Santos, Polliana Batista dos Silva, Audrey Borghi Mendes, Renata Gonçalves
URI:	https://repositorio.ufscar.br/handle/ufscar/15569
Outros identificadores:	https://doi.org/10.1097/hcr.0000000000000483
Fomento:	Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
Número do Projeto:	Processo nº 2018/03314-0, Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) Processo nº 2018/00860-3, Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) Processo nº 2015/26501–1, Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) Processo nº 2015/12763-4, Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) Código de Financiamento 001 - CAPES
Termo de uso:	Attribution-NonCommercial-NoDerivs 3.0 Brazil
Data:
Data de Disponibilização:	9-Fev-2022
Formato:
Tipo:	Dataset
Editora / Evento / Instituição:	Universidade Federal de São Carlos
Idioma :
Aparece nas coleções:	Repositório dados - UFSCar

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